Medically reviewed by Drugs.com. Last updated on Apr 8, 2022.
Commonly used brand name(s)
In the U.S.
- Adasuve
Available Dosage Forms:
- Powder
Therapeutic Class: Antipsychotic
Chemical Class: Dibenzoxazepine
Uses for loxapine
Inhaled loxapine is used to treat acute agitation in adult patients with schizophrenia or bipolar I disorder (type of depression). It works in the brain to increase levels of dopamine and serotonin, which are chemicals that help regulate agitation, schizophrenia, and depression. Loxapine is an antipsychotic medicine.
Loxapine is available only under a special restricted distribution program called the Adasuve® REMS program.
Before using loxapine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For loxapine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to loxapine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of inhaled loxapine in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies have not been performed on the relationship of age to the effects of inhaled loxapine in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of inhaled loxapine in the elderly. However, loxapine should not be used for behavioral problems in older adults with dementia.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interact...