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Lubiprostone
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Lubiprostone

Generic name: lubiprostone [ loo-bee-PROS-tone ]
Brand name: Amitiza
Dosage form: oral capsule (24 mcg; 8 mcg)
Drug class:Chloride channel activators

Medically reviewed by Drugs.com on Oct 19, 2021. Written by Cerner Multum.

What is lubiprostone?

Lubiprostone is used to treat chronic constipation, or constipation caused by opioid pain medicine.

Lubiprostone may also be used to treat irritable bowel syndrome in women with constipation as the main symptom.

Lubiprostone may also be used for purposes not listed in this medication guide.

Warnings

Stop taking lubiprostone and call your doctor if you feel light-headed every time you take lubiprostone or if you have severe diarrhea.

Before taking this medicine

You should not use lubiprostone if you have a blockage in your digestive tract, or if you have severe diarrhea.

Tell your doctor if you have ever had liver disease.

Tell your doctor if you are pregnant or breastfeeding.

If you are breastfeeding, tell your doctor if you notice diarrhea in the nursing baby.

Not approved for use by anyone younger than 18 years old.

How should I take lubiprostone?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take with food and water.

Swallow the capsule whole and do not crush, chew, break, or open it.

You may have tightness in your chest or feel short of breath within 1 hour after taking lubiprostone. This side effect should go away within 3 hours, but i...