Lumasiran (Subcutaneous)

Medically reviewed by Drugs.com. Last updated on Jan 1, 2022.

Commonly used brand name(s)

In the U.S.

• Oxlumo

Available Dosage Forms:

• Solution

Therapeutic Class: Renal-Urologic Agent

Uses for lumasiran

Lumasiran injection is used to treat primary hyperoxaluria (high oxalic acid in the urine) type 1 (PH1) to lower oxalic acid in the urine.

Lumasiran is to be given only by or under the supervision of your doctor.

Before using lumasiran

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lumasiran, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to lumasiran or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of lumasiran injection in children. Safety and efficacy have been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of lumasiran injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of lumasiran

A nurse or other trained health professional will give you lumasiran in a medical facility. It is given as a shot under your skin, usually in the stomach, thigh, or the side or back of the upper arms.

Missed dose

Call your doctor or pharmacist for instructions.

Precautions while using lumasiran

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