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Lupkynis
  • Treatments
  • Lupus Nephritis

Lupkynis

Generic name:voclosporinVOE-kloe-SPOR-in ]
Drug class:Calcineurin inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on Mar 22, 2021.

What is Lupkynis?

Lupkynis is a calcineurin-inhibitor immunosuppressant medicine.

Lupkynis is a prescription medicine used together with other medicines to treat kidney problems (active lupus nephritis) in adults with system lupus erythematous (SLE).

Lupkynis should not be taken with a medicine called cyclophosphamide. Talk with your healthcare provider if you are not sure if you take this medicine.

Lupkynis is supplied as an oval pink/orange capsule, imprinted on one side with VCS in white ink, packed in aluminum blisters.

Warnings

Taking Lupkynis may increase your risk of certain cancers such as skin cancer or lymphoma.

Voclosporin affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, sweating, cough, skin sores, muscle aches, or other flu-like symptoms.

Do not take Lupkynis with medicines known as strong CYP3A4 inhibitors such as ketoconazole, itraconazole, and clarithromycin.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

You should not use Lupkynis if you are allergic to voclosporin.

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with Lupkynis. Your doctor may change your treatment plan if you also use: