Lurbinectedin
Generic name: lurbinectedin [ LOOR-bin-EK-te-din ]
Brand name: Zepzelca
Dosage form: intravenous powder for injection (4 mg)
Drug class:Alkylating agents
What is lurbinectedin?
Lurbinectedin is used to treat small cell lung cancer that has spread to other parts of the body (metastatic).
Lurbinectedin is given after a platinum cancer medicine did not work or has stopped working.
Lurbinectedin may also be used for purposes not listed in this medication guide.
Warnings
Lurbinectedin can increase your risk of bleeding or infection. You will need frequent medical tests.
Before taking this medicine
Tell your doctor if you have ever had:
liver or kidney disease;
You may need to have a negative pregnancy test before starting this treatment.
Lurbinectedin can harm an unborn baby if the mother or the father is using lurbinectedin.
If you are a woman, do not use lurbinectedin if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using lurbinectedin.
Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.
How should I take lurbinectedin?
Before you receive a dose of lurbinectedin, you may need a blood test to check your liver function.
Lurbinectedin is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take at least 1 hour to complete.
You may be given infusions of other medications to help prevent nausea and vomiting.
Lurbinectedin is usually given once every 21 days.
Lurbinectedin can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.
Your doctor will determine how long to treat with you with this medicine.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your lurbinectedin injection.
What happens if I overdose?
Since lurbinectedin is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while taking lurbinectedin?
Grapefruit may interact with lurbinectedin and lead to unwanted side effec...
