Luspatercept
Generic name: luspatercept [ lus-PAT-er-sept ]
Brand name: Reblozyl
Dosage form: subcutaneous powder for injection (25 mg; 75 mg)
Drug class:Miscellaneous erythropoiesis agents
What is luspatercept?
Luspatercept is for use in adults with a blood disorder called beta thalassemia, in which the body does not produce enough hemoglobin (HEEM o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs.
Luspatercept is used to treat anemia (lack of red blood cells) in adults with beta thalassemia who need to have regular red blood cell transfusions.
Luspatercept may also be used for purposes not listed in this medication guide.
Warnings
Before using luspatercept tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.
Before taking this medicine
Tell your doctor if you have ever had:
spleen removal surgery;
a stroke or blood clot;
diabetes;
if you smoke; or
if you use birth control pills or hormone replacement therapy.
Tell your doctor if you are pregnant or could become pregnant. Luspatercept may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using luspatercept and for at least 3 months after your last dose.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose.
How is luspatercept given?
Luspatercept is injected under the skin, usually once every 3 weeks.
A healthcare provider will give you this injection.
Before each injection, your will need a blood test to check your hemoglobin levels. Be sure to tell your healthcare provider when you last had a blood transfusion.
Luspatercept doses are based on weight. Your dose needs may change if you gain or lose weight.
Your blood pressure will need to be checked often.
You may be given other medications to help control your blood pressure. Keep using this medicine for as long as your doctor has prescribed.
What happens if I miss a dose?
You should receive an injection as soon as you can, and then go back to your regular schedule. At least 3 weeks should pass between each injection.
