Lutetium Lu 177 dotatate

Generic name: lutetium Lu 177 dotatate [ loo-TEE-shee-um-LOO-177 DOE-ta-tate ]
Brand name: Lutathera
Dosage form: intravenous solution (370 MBq/mL)
Drug class:Therapeutic radiopharmaceuticals

Medically reviewed by Drugs.com on May 2, 2022. Written by Cerner Multum.

What is lutetium Lu 177 dotatate?

Lutetium Lu 177 dotatate is a radioactive medicine that binds itself to a specific part of certain tumor cells, allowing the radiation to enter and destroy those cells.

Lutetium Lu 177 dotatate is used to treat certain cancers of the digestive tract, including the stomach, pancreas, and intestines.

Lutetium Lu 177 dotatate may also be used for purposes not listed in this medication guide.

Warnings

Do not become pregnant or breast-feed a baby while receiving lutetium Lu 177 dotatate.

Both men and women using lutetium Lu 177 dotatate should use effective birth control to prevent pregnancy. Lutetium Lu 177 dotatate can harm an unborn baby or cause birth defects if the mother or father is using this medicine.

Before taking this medicine

You should not use lutetium Lu 177 dotatate if you are pregnant or breast-feeding.

Lutetium Lu 177 dotatate can harm an unborn baby or cause birth defects if the mother or the father is receiving this medicine.

• If you are a woman, use effective birth control to prevent pregnancy while you are receiving this medicine and for at least 7 months after your last dose.

• If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.

• Tell your doctor right away if a pregnancy occurs while either the mother or the father is receiving lutetium Lu 177 dotatate.

Do not breast-feed while receiving lutetium Lu 177 dotatate, and for at least 4 months after your last dose.

Tell your doctor if you have ever had:

• kidney disease;

• liver disease;

• diabetes;

• high blood pressure; or

• any type of radiation treatment.

Lutetium Lu 177 dotatate may cause other types of cancer, such as leukemia. Ask your doctor about this risk.

This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because lutetium Lu 177 dotatate may harm the baby if a pregnancy does occur.

How is lutetium Lu 177 dotatate given?

Lutetium Lu 177 dotatate is given as an infusion into a vein. A healthcare provider will give you this injection once every 8 weeks for a total of 4 doses.

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