Luzu Cream

Generic name: luliconazole
Dosage form: cream
Drug class:Topical antifungals

Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.

Indications and Usage for Luzu Cream

LUZU (luliconazole) Cream, 1% is indicated for the topical treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum and Epidermophyton floccosum.

Luzu Cream Dosage and Administration

For topical use only. Luzu Cream, 1% is not for ophthalmic, oral, or intravaginal use.

•

When treating interdigital tinea pedis, a thin layer of Luzu Cream, 1% should be applied to the affected area and approximately 1 inch of the immediate surrounding area(s) once daily for 2 weeks.

•

When treating tinea cruris or tinea corporis, Luzu Cream, 1% should be applied to the affected area and approximately 1 inch of the immediate surrounding area(s) once daily for 1 week.

Dosage Forms and Strengths

Cream, 1%. Each gram of Luzu Cream, 1% contains 10 mg of luliconazole in a white cream base.

Contraindications

None.

Adverse Reactions

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

In three Phase 3 clinical trials, 616 subjects were exposed to Luzu Cream, 1%: 305 with interdigital tinea pedis and 311 subjects with tinea cruris. Subjects with interdigital tinea pedis or tinea cruris applied Luzu Cream, 1% or vehicle cream once daily for 14 days or 7 days, respectively, to affected and adjacent areas. During clinical trials with Luzu Cream, 1%, the most common adverse reactions were application site reactions which occurred in less than 1% of subjects in both the LUZU and vehicle arms. Most adverse reactions were mild in severity.

A post-approval clinical trial was conducted in 75 subjects age 2 to <18 years old with tinea...