Lynparza
Generic name:olaparib [ oh-LAP-a-rib ]
Drug class:PARP inhibitors
What is Lynparza?
Lynparza is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Lynparza is used to treat ovarian cancer, fallopian tube cancer, or peritoneal cancer in women with a certain abnormal inherited gene. This medicine is sometimes given when the cancer has come back after treatment with other medications.
Lynparza is used to treat HER2-negative breast cancer that has spread to other parts of the body before or after prior chemotherapy or hormonal treatment.
Lynparza is used to treat pancreatic cancer in patients with a certain abnormal inherited gene.
Lynparza is also used to treat prostate cancer with certain inherited or acquired abnormal genes.
Lynparza is sometimes used only if your cancer has a specific genetic marker (an abnormal "BRCA" or "HRR" gene). Your doctor will test you for this gene.
Warnings
Lynparza affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, weakness, tiredness, trouble breathing, easy bruising or bleeding, blood in your urine or stools, or weight loss.
You will need weekly or monthly blood tests, and your cancer treatments may be delayed based on the results.
Some people who take olaparib with a gonadotropin-releasing hormone (GnRH) medicine may develop a blood clot in the leg or in the lung. Call your doctor if you have pain or swelling in your arm or leg, shortness of breath, chest pain, rapid breathing, or fast heartbeats.
Lynparza may also cause serious lung problems. Call your doctor if you have chest pain, wheezing, trouble breathing, or a new or worsening cough.
Before taking this medicine
You should not use Lynparza if you are allergic to olaparib.
To make sure Lynparza is safe for you, tell your doctor if you have ever had:
lung disease, breathing problems; or
kidney disease.
Olaparib can harm an unborn baby or cause a miscarriage if the mother or the father is using this medicine.
If you are a woman, do not use this medicine if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. ...
