Amlodipine, hydrochlorothiazide, and valsartan

Generic name: amlodipine, hydrochlorothiazide, and valsartan [ am-LOE-di-peen, HYE-droe-klor-oh-THYE-a-zide, val-SAR-tan ]
Brand name: Exforge HCT
Dosage form: oral tablet (10 mg-12.5 mg-160 mg; 10 mg-25 mg-160 mg; 10 mg-25 mg-320 mg; 5 mg-12.5 mg-160 mg; 5 mg-25 mg-160 mg)
Drug class:Miscellaneous antihypertensive combinations

Medically reviewed by Drugs.com on Feb 12, 2021. Written by Cerner Multum.

What is amlodipine, hydrochlorothiazide, and valsartan?

Amlodipine is a calcium channel blocker. Hydrochlorothiazide is a thiazide diuretic (water pill). Valsartan is an angiotensin II receptor blocker (sometimes called an ARB).

Amlodipine, hydrochlorothiazide, and valsartan is a combination medicine used to treat high blood pressure (hypertension).

amlodipine, hydrochlorothiazide, and valsartan is usually given after other blood pressure medication did not work.

Amlodipine, hydrochlorothiazide, and valsartan may also be used for purposes not listed in this medication guide.

Warnings

You should not take this medicine if you are allergic to sulfa drugs, or if you are unable to urinate.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use amlodipine, hydrochlorothiazide, and valsartan together with any medication that contains aliskiren (a blood pressure medicine).

Before taking this medicine

You should not use this medicine if you are allergic to amlodipine, hydrochlorothiazide, or valsartan, or:

• if you are allergic to any sulfa drug; or

• if you are unable to urinate.

If you have diabetes, do not use amlodipine, hydrochlorothiazide, and valsartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking this medicine with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

• heart problems;

• an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

• high blood levels of calcium;

• kidney disease (or if you are on dialysis);

• liver disease;

• glaucoma;

• gout, or increased uric acid in your blood;

• lupus;

• gallstones; or

• a penicillin allergy....