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Mafenide topical
  • Treatments
  • Burns
  • External

Mafenide topical

Generic name: mafenide topical [ MAF-en-ide ]
Brand name: Sulfamylon
Dosage forms: topical cream (85 mg/g); topical powder for reconstitution (5%)
Drug class:Topical antibiotics

Medically reviewed by Drugs.com on Sep 7, 2021. Written by Cerner Multum.

What is mafenide?

Mafenide is an antibiotic that fights bacteria in the body.

Mafenide topical (for the skin) is used to prevent infection in severe burn wounds.

Mafenide may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use mafenide topical if you are allergic to mafenide.

To make sure mafenide topical is safe for you, tell your doctor if you have:

  • kidney disease;

  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;

  • asthma or sulfite allergy; or

  • if you are allergic to sulfa drugs.

FDA pregnancy category C. It is not known whether mafenide topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether mafenide topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is mafenide used?

Your doctor will determine the correct amount and type of mafenide to use. You will receive this medication in a hospital or burn unit setting.

Mafenide cream is usually applied to the burn wound once or twice a day. The wound should be kept covered with this medicine at all times during treatment.

Mafenide powder is usually mixed together with a saline solution and applied over a gauze dressing using a syringe or irrigation tube. Mafenide is usually applied several times per day in order to keep the bandaging wet.

What happens if I miss a dose?

Because you will receive mafenide topical in a clinical setting, you are not likely to miss a dose.