Generic name:bupivacaine hydrochloride
Dosage form: injection, solution
Drug class:Local injectable anesthetics
Medically reviewed by Drugs.com. Last updated on Jan 1, 2022.
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HIGHLIGHTS OF PRESCRIBING INORMATION
These highlights do not include all the information needed to use Marcaine™ and Marcaine™ WITH EPINEPHRINE safely and effectively. See full prescribing information for Marcaine™ and Marcaine™ WITH EPINEPHRINE.
Marcaine™ (bupivacaine hydrochloride) injection, for infiltration, perineural, caudal, epidural, or retrobulbar use
Marcaine™ WITH EPINEPHRINE (bupivacaine hydrochloride and epinephrine) injection, for infiltration, perineural, caudal, or epidural use
Initial U.S. Approval: 1972
WARNING: RISK OF CARDIAC ARREST WITH USE OF Marcaine IN OBSTETRICAL ANESTHESIA
SEE FULL PRESCRIBING INFORMATION FOR COMPLETE BOXED WARNING.
There have been reports of cardiac arrest with difficult resuscitation or death during use of Marcaine for epidural anesthesia in obstetrical patients. In most cases, this has followed use of the 0.75% (7.5 mg/mL) concentration. Resuscitation has been difficult or impossible despite apparently adequate preparation and appropriate management. Cardiac arrest has occurred after convulsions resulting from systemic toxicity, pr
