Mavenclad

Generic name:cladribine (oral) [ KLAD-ri-been ]
Drug class:Antimetabolites

Medically reviewed by Judith Stewart, BPharm. Last updated on Apr 21, 2022.

What is Mavenclad?

Mavenclad is a purine antimetabolite that interferes with enzymes that are necessary for DNA synthesis.

Mavenclad is used to treat relapsing multiple sclerosis (MS) in adults. This medicine will not cure MS, it will only decrease the frequency of relapse symptoms.

Mavenclad is usually given after other treatments have failed.

Warnings

Do not take Mavenclad if you are pregnant. Both men and women should use effective birth control to prevent pregnancy while taking Mavenclad, and for 6 months after the last dose.

If you use birth control pills or other hormonal forms (implants, skin patches, vaginal rings), also use a barrier form of birth control (condom, diaphragm, cervical cap, contraceptive sponge) to prevent pregnancy while taking Mavenclad and for at least 4 weeks after your treatment course ends.

Taking cladribine may increase your risk of developing certain cancers.

Before taking this medicine

You should not take Mavenclad if you are allergic to cladribine, or if you have:

• cancer;

• an active infection such as tuberculosis or hepatitis B or C;

• HIV or AIDS; or

• if you are pregnant or breastfeeding.

To make sure Mavenclad is safe for you, tell your doctor if you have ever had:

• an active or chronic infection;

• heart problems;

• weak immune system (caused by disease or by using certain medicine);

• liver or kidney disease;

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