Generic name:casimersen [ KAS-i-MER-sen ]
Drug class:Miscellaneous uncategorized agents
What is Amondys 45?
Amondys 45 is used to treat Duchenne muscular dystrophy in adults and children who have a certain gene mutation. Your doctor will test you for this gene mutation.
Amondys 45 was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to Amondys 45, but further studies are needed.
Amondys 45 may also be used for purposes not listed in this medication guide.
Warnings
Before using Amondys 45 tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.
Before taking this medicine
Tell your doctor if you have ever had kidney problems.
Tell your doctor if you are pregnant or breastfeeding.
How should I take Amondys 45?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Amondys 45.
Amondys 45 is given as an infusion into a vein, usually once per week. A healthcare provider will give you this injection.
Amondys 45 must be given slowly, and the infusion can take 35 to 60 minutes to complete.
Your kidney function may need to be checked while you are using this medicine.
Amondys 45 doses are based on weight. Your dose needs may change if you gain or lose weight.