Mayzent

Generic name:siponimod [ sye-POE-ni-mod ]
Drug class:Selective immunosuppressants

Medically reviewed by Judith Stewart, BPharm. Last updated on May 4, 2022.

What is Mayzent?

Mayzent is a prescription medicine used to treat relapsing multiple sclerosis (MS) in adults.

Mayzent will not cure MS, it will only decrease the frequency of relapse symptoms.

Mayzent is used only if you have a specific genotype. Your doctor will test you for this genotype.

Warnings

You should not use Mayzent if you have a serious heart condition such as "AV block," sick sinus syndrome and no pacemaker, or if you've recently had heart block, heart failure, a heart rhythm disorder, chest pain, heart attack, or stroke.

Mayzent can slow your heart rate when you start taking it. You will receive your first dose in a setting where your heart rhythm can be monitored. If you miss any doses, you may also need to restart Mayzent under medical observation.

You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, vomiting, confusion, neck stiffness, increased sensitivity to light, or problems with coordination, thought, vision, or muscle movement.

Before taking this medicine

You should not use Mayzent if you are allergic to siponimod, or if you have certain serious heart conditions, especially:

• "AV block" (2nd or 3rd degree);

• sick sinus syndrome (unless you have a pacemaker);

• recent (within the past 6 months) heart failure, heart attack, stroke, "mini-stroke" or TIA, chest pain (unstable angina), or other serious heart problem.