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Medroxyprogesterone injection
  • Treatments
  • Abnormal Uterine Bleeding
  • Medroxyprogesterone (injection)

Medroxyprogesterone (injection)

Generic name: medroxyprogesterone (injection) [ me-DROX-ee-proe-JES-ter-one ]
Brand names: Depo-Provera, Depo-Provera Contraceptive, depo-subQ provera 104
Dosage forms: intramuscular suspension (150 mg/mL; 400 mg/mL); subcutaneous suspension (104 mg/0.65 mL)
Drug classes:Contraceptives, Hormones / antineoplastics, Progestins

Medically reviewed by Drugs.com on Apr 7, 2021. Written by Cerner Multum.

What is medroxyprogesterone?

Medroxyprogesterone is a form of progesterone, a female hormone that prevents ovulation (the release of an egg from an ovary). medroxyprogesterone also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Medroxyprogesterone is used as contraception to prevent pregnancy. It is also used to reduce pain caused by endometriosis.

Medroxyprogesterone may also be used for purposes not listed in this medication guide.

Warnings

You should not use medroxyprogesterone if you have: undiagnosed vaginal bleeding, liver disease, breast cancer, if you are pregnant, or if you have ever had a stroke or blood clot.

Medroxyprogesterone can decrease the calcium stored in your bones, which may cause bone loss (osteoporosis) when the medicine is used over long periods of time. Bone loss may not be reversible.

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