Dosage form: rectal suppository
Drug class:5-aminosalicylates
Medically reviewed by Drugs.com. Last updated on Dec 1, 2021.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
1. INDICATIONS AND USAGE
Mesalamine suppositories are indicated in adults for the treatment of mildly to moderately active ulcerative colitis.
2. DOSAGE AND ADMINISTRATION
The recommended dosage of mesalamine suppositories in adults is 1000 mg administered rectally once daily at bedtime for 3 to 6 weeks depending on symptoms and sigmoidoscopic findings. Safety and effectiveness of mesalamine suppositories beyond 6 weeks have not been established.
Administration Instructions
- Evaluate renal function prior to initiation of Mesalamine Suppository therapy [see Warnings and Precautions (5.1)].
- Do not cut or break the suppository.
- Retain the suppository for one to three hours or longer, if ...
