Mesnex Injection
Generic name:mesna
Dosage form: injection, solution
Drug class:Antineoplastic detoxifying agents
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for Mesnex Injection
MESNEX is indicated as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis.
Limitation of Use:
MESNEX is not indicated to reduce the risk of hematuria due to other pathological conditions such as thrombocytopenia.
Mesnex Injection Dosage and Administration
Intravenous Dosing
MESNEX may be given on a fractionated dosing schedule of three bolus intravenous injections as outlined below.
Mesnex Injection is given as intravenous bolus injections in a dosage equal to 20% of the ifosfamide dosage weight by weight (w/w) at the time of ifosfamide administration and 4 and 8 hours after each dose of ifosfamide. The total daily dose of MESNEX is 60% of the ifosfamide dose. The recommended dosing schedule is outlined below in Table 1.
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MEDICAL DEPARTMENTS
Cardiology
Pediatrics
Diabetes Care
Pre-natal Care
Ultrasound Echocardiogram
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