Metformin and sitagliptin
Generic name: metformin and sitagliptin [ met-FOR-min-and-SI-ta-glip-tin ]
Brand names: Janumet, Janumet XR
Dosage forms: oral tablet (1000 mg-50 mg; 500 mg-50 mg); oral tablet, extended release (1000 mg-100 mg; 1000 mg-50 mg; 500 mg-50 mg)
Drug class:Antidiabetic combinations
What is metformin and sitagliptin?
Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels.
Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.
Metformin and sitagliptin is a combination medicine that is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. metformin and sitagliptin is not for treating type 1 diabetes.
Metformin and sitagliptin may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.
Before taking this medicine
You should not use metformin and sitagliptin if you are allergic to metformin or sitagliptin (Januvia), or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).
Tell your doctor if you have ever had:
kidney disease (your kidney function may need to be checked before and while you are taking this medicine);
heart disease;
high triglycerides (a type of fat in the blood);
gallstones; or
You may develop lactic acidosis, a dangerous build-up of lactic acid in your b...
