Methotrexate (injection)

Generic name: methotrexate (injection) [ meth-oh-TREX-ate ]
Brand names: EmGyn Kit, Methotrexate Sodium, Preservative Free, Otrexup, Rasuvo
Dosage forms: injectable powder for injection (1 g); injectable solution (25 mg/mL; 25 mg/mL preservative-free); intramuscular solution (25 mg/mL preservative-free); subcutaneous solution (10 mg/0.2 mL; 10 mg/0.4 mL; 12.5 mg/0.25 mL; 12.5 mg/0.4 mL; 12.5 mg/0.5 mL; 15 mg/0.3 mL; 15 mg/0.4 mL; 15 mg/0.6 mL; 17.5 mg/0.35 mL; 17.5 mg/0.4 mL; 17.5 mg/0.7 mL; 20 mg/0.4 mL; 20 mg/0.8 mL; 22.5 mg/0.4 mL; 22.5 mg/0.45 mL; 22.5 mg/0.9 mL; 25 mg/0.4 mL; 25 mg/0.5 mL; 25 mg/mL; 30 mg/0.6 mL; 7.5 mg/0.15 mL; 7.5 mg/0.3 mL; 7.5 mg/0.4 mL)
Drug classes:Antimetabolites, Antipsoriatics, Antirheumatics, Other immunosuppressants

Medically reviewed by Drugs.com on Feb 18, 2022. Written by Cerner Multum.

What is methotrexate injection?

Methotrexate is used to treat leukemia and certain types of cancer of the breast, skin, head and neck, or lung.

Methotrexate is also used to treat severe psoriasis and rheumatoid arthritis in adults, and to treat active polyarticular-course juvenile rheumatoid arthritis in children.

Methotrexate is often used when other medicines have not been effective.

Methotrexate may also be used for purposes not listed in this medication guide.

Warnings

Methotrexate should not be used during pregnancy to treat arthritis or psoriasis. Methotrexate is sometimes used to treat cancer during pregnancy. Tell your doctor if you...