Methyldopate

Generic name: Methyldopate hydrochloride
Dosage form: injection, solution
Drug class:Antiadrenergic agents, centrally acting

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

Methyldopate Description

Methyldopate HCl Injection, USP, is an antihypertensive agent for intravenous use. Sterile, nonpyrogenic.

Methyldopate hydrochloride [levo-3-(3,4-dihydroxyphenyl)-2-methylalanine, ethyl ester hydrochloride] is the ethyl ester of methyldopa, supplied as the hydrochloride salt with a molecular weight of 275.73. Methyldopate hydrochloride is more soluble and stable in solution than methyldopa and is the preferred form for intravenous use.

The molecular formula for Methyldopate hydrochloride is C12H17NO4·HCl and the structural formula is:

Each mL contains:

Methyldopate Hydrochloride ..... 50 mg
Citric Acid (Anhydrous) ..... 5 mg
Edetate Disodium ..... 0.5 mg
Monothioglycerol ..... 2 mg
Water for Injection .....q.s. to 1 mL

Methylparaben 1.5 mg and Propylparaben 0.2 mg added as preservatives, Sodium Bisulfite 3.2 mg added as an antioxidant. pH adjusted with Sodium Hydroxide and/or Hydrochloric Ac