Metozolv ODT
Generic name:metoclopramide [ MET-oh-KLOE-pra-mide ]
Drug classes:GI stimulants, Miscellaneous antiemetics
Medically reviewed by Drugs.com. Last updated on Mar 29, 2022.
The Metozolv ODT brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Metozolv ODT?
Metozolv ODT (metoclopramide orally disintegrating tablets) increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.
Metozolv ODT is is a prescription medicine used in adults for 4 to 12 weeks to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief.
Metozolv ODT is also used to treat gastroparesis (slow stomach emptying) in people with diabetes, which can cause heartburn and stomach discomfort after meals.
Metozolv ODT is supplied as a tablet that melts in your mouth.
Warnings
Do not use Metozolv ODT if you've ever had muscle movement problems after using metoclopramide or similar medicines, or if you've had a movement disorder called tardive dyskinesia. You also should not use this medicine if you've had stomach or intestinal problems (a blockage, bleeding, or a hole or tear), epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma).
NEVER USE METOZOLV ODT IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).
Before you take Metozolv ODT, tell your doctor if you have kidney or liver disease, congestive heart failure, high blood pressure, diabetes, Parkinson's disease, or a history of depression.
Do not drink alcohol. It can increase some of the side effects of metoclopramide.
Stop using Metozolv ODT and call your doctor at once if you have tremors or uncontrolled muscle movements, fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing, depressed mood, thoughts of suicide or hurting yourself, hallucinations, anxiety, agitation, seizure, or jaundice (yellowing of your skin or eyes).
Before taking this medicine
You should not use Metozolv ODT if you are allergic to metoclopramide, or if you have:
tardive dyskinesia (a disorder of involuntary movements);
stomach or intestinal problems such as a blockage, bleeding, or...