Moclobemide (Oral)
Pharmacologic Class: Reversible inhibitor of Monoamine Oxidase A (MAO-A) (RIMA)
Uses for moclobemide
Moclobemide is a type of monoamine oxidase (MAO) inhibitor used to treat certain types of mental depression. It works by reversibly blocking the action of a chemical substance known as monoamine oxidase A (MAO-A) in the nervous system.
Although moclobemide is very effective for certain patients, it may also cause some unwanted reactions if taken the wrong way. It is very important to avoid certain beverages and medicines while you are using moclobemide. Your doctor may provide a list as a reminder of which products you should avoid.
Moclobemide is available only with your doctor's prescription.
Before using moclobemide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For moclobemide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to moclobemide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Studies on moclobemide have been done only in adult patients, and there is no specific information comparing use of moclobemide in children with use in other age groups.
Geriatric
Older adults are especially sensitive to the effects of moclobemide. This may increase the chance of side effects during treatment. Dizziness or lightheadedness may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to these effects.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking moclobemide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using moclobemide with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Amitriptyline
- Amoxapine
- Amphetamine
- Apraclonidine
- Benzphetamine
- Brimonidine
- Bupropion
- Carbamazepine
- Carbidopa
- Carbinoxamine
- Citalopram
- Clomipramine
- Codeine
- Cyclobenzaprine
- Cyproheptadine
- Desipramine
- Desvenlafaxine
- Deutetrabenazine
- Dexfenfluramine
- Dexmethylphenidate
- Dextroamphetamine
- Dextromethorphan
- Diethylpropion
- Dothiepin
- Doxepin
- Doxylamine
- Duloxetine
- Eliglustat
- Escitalopram
- Fenfluramine
- Fluoxetine
- Fluvoxamine
- Guanadrel
- Guanethidine
- Hydroxytryptophan
- Imipramine
- Isometheptene
- Levodopa
- Levomethadyl
- Levomilnacipran
- Lisdexamfetamine
- Lofepramine
- Maprotiline
- Mavacamten
- Mazindol
- Meperidine
- Methamphetamine
