Antinaus 50
Generic name:promethazine (injection route, intravenous route) [ proe-METH-a-zeen ]
Drug classes:Antihistamines, Phenothiazine antiemetics
Medically reviewed by Drugs.com. Last updated on Apr 24, 2022.
Respiratory Depression – PediatricsPromethazine hydrochloride injection should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine in pediatric patients less than 2 years of age. Caution should be exercised when administering promethazine hydrochloride injection to pediatric patients 2 years of age and older .Severe Tissue Injury, Including GangrenePromethazine hydrochloride injection can cause severe chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and gangrene. In some cases , surgical intervention, including fasciotomy, skin graft, and/or amputation have been required .Due to the risks of intravenous injection, the preferred route of administration of promethazine hydrochloride injection is deep intramuscular injection. Subcutaneous injection is contraindicated .
Commonly used brand name(s)
In the U.S.
- Antinaus 50
- Phenergan
- Promacot
- Prorex
Available Dosage Forms:
- Solution
Therapeutic Class: Gastrointestinal Agent
Pharmacologic Class: Antihistamine
Chemical Class: Aliphatic
Uses for Antinaus 50
Promethazine injection is used to relieve or prevent some types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult.
Promethazine is also used to prevent and control motion sickness, nausea, vomiting, and dizziness. In addition, it may be used to help people go to sleep and control their pain or anxiety before or after surgery or other procedures.
Promethazine may also be used for other conditions as determined by your doctor.
This medicine is only available with your doctor's prescription.
Before using Antinaus 50
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
