Poly Hist PD

Generic name: pyrilamine maleate, chlorpheniramine maleate and phenylephrine hydrochloride
Dosage form: liquid
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Poly Hist PD

Antihistamine / Decongestant
Sugar Free / Alcohol Free / Dye Free

DESCRIPTION: Poly Hist PD is a sugar free, alcohol free, dye free, clear and colorless liquid with a
bubble gum odor and flavor. Each 5 mL (1 teaspoonful) contains:
Pyrilamine Maleate..... 12.5 mg
Chlorpheniramine Maleate..... 2 mg
Phenylephrine HCl..... 7.5 mg

Pyrilamine Maleate is an antihistamine that occurs as a white crystalline powder, usually having a faint odor.
It is very soluble in water, freely soluble in alcohol and chloroform, and slightly soluble in ether and benzene.
The chemical name is 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N', N'dimethyl-N-2-pyridinyl-, (Z)-2-
butenedioate (1:1). Its structural formula is as follows:



Chlorpheniramine Maleate is an antihistaminic that occurs as a white, odorless crystalline powder. Its solutions
have a pH between 4 and 5. It is freely soluble in water, soluble in alcohol and chloroform, and slightly soluble
in ether and benzene. The chemical name is 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-,
(Z)-2-butenedioate (1:1). Its structural formula is as follows:


Phenylephrine hydrochloride is an adrenergic that occurs as white or practically white, odorless crystals, having
a bitter taste. It is freely soluble in water and alcohol. It is affected by light. The chemical name is benzenemethanol, 3-hydroxy-alpha[(methylamino)methyl]-, hydrochloride (R)-. Its structural formula is as follows: