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Rolapitant
  • Treatments
  • Nausea/Vomiting
  • Chemotherapy Induced

Rolapitant

Generic name: rolapitant (oral) [ roe-LA-pi-tant ]
Brand name: Varubi
Dosage form: oral tablet (90 mg)
Drug class:NK1 receptor antagonists

Medically reviewed by Drugs.com on Nov 5, 2020. Written by Cerner Multum.

What is rolapitant?

Rolapitant is used together with other medicines to prevent nausea and vomiting caused by cancer chemotherapy.

Rolapitant may also be used for purposes not listed in this medication guide.

Warnings

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

Some medicines can cause unwanted or dangerous effects when used with rolapitant. Your doctor may change your treatment plan if you also use:

Rolapitant is not approved for use by anyone younger than 2 years old.

Tell your doctor if you have ever had:

  • liver disease; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

Tell your doctor if you are pregnant or breastfeeding.

rolapitant may affect fertility (your ability to have children) for a short time.

How should I take rolapitant?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Rolapitant is usually given on Day 1 of your chemotherapy treatment.

You may take rolapitant with or without food.

You should not take rolapitant more than once every 14 days.

You will be given other medication to prevent nausea or vomiting. Keep using these medicines for as long as your doctor has prescribed.

Store at room temperature away from moisture and heat. Keep each tablet in the foil blister pack until you are ready to take the medicine.

What happens if I miss a dose?

Call your doctor for instructions if you forget to take the tablets at the correct time before chemotherapy. The timing of your rolapitant dose is important for rolapitant to be effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid after taking rolapitant?

For at least 1 month after you use rolapitant, avoid using any cough or cold medicine that contains

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