Tobramycin and dexamethasone (Ophthalmic)

Medically reviewed by Drugs.com. Last updated on Feb 11, 2022.

Commonly used brand name(s)

In the U.S.

• Tobradex
• Tobradex ST

In Canada

• Tobradex Ointment
• Tobradex Suspension

Available Dosage Forms:

• Suspension
• Ointment

Therapeutic Class: Aminoglycoside/Corticosteroid Combination

Pharmacologic Class: Adrenal Glucocorticoid

Chemical Class: Aminoglycoside

Uses for tobramycin and dexamethasone

Tobramycin and dexamethasone is a combination of an antibiotic and a corticosteroid. It is used in the eye to prevent permanent damage, which may occur with certain eye problems.

Tobramycin and dexamethasone is available only with your doctor's prescription.

Before using tobramycin and dexamethasone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tobramycin and dexamethasone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to tobramycin and dexamethasone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on tobramycin and dexamethasone have been done only in adult patients, and there is no specific information comparing use of ophthalmic tobramycin and dexamethasone in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ophthalmic tobramycin and dexamethasone in the elderly with use in other age groups.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking tobramycin and dexamethasone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using tobramycin and dexamethasone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Artemether
• Ataluren
• Desmopressin
• Praziquantel
• Rilpivirine
• Rotavirus Vaccine, Live

Using tobramycin and dexamethasone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abametapir
• Aceclofenac
• Acemetacin
• Alcuronium
• Aldesleukin
• Alfentanil
• Amiodarone
• Amtolmetin Guacil
• Apaluta...