Brompheniramine Maleate Drops
Dosage form: oral liquid
Drug class:Antihistamines
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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Brompheniramine Maleate Drops Description
Brompheniramine Maleate 1 mg Drops is an antihistaminic drop for oral administration containing the following amounts of active ingredients in each 1 mL dropperful:Brompheniramine Maleate, USP …….....…………………. 1 mg
Inactive Ingredients: Banana Flavor, Citric Acid, Glycerin, Propylene Glycol, Purified Water, Saccharin Sodium, Sodium Benzoate, Sorbitol, Strawberry Flavor, and Xanthan Gum.
Brompheniramine maleate is an antihistamine having the chemical name 2-pyridinepropanamine, -[4-bromophenyl)-N,N-dimethyl-,(±)-,[Z]-2-butenedioate (1:1) with the following chemical structure:
Brompheniramine Maleate Drops - Clinical Pharmacology
Brompheniramine MaleateBrompheniramine Maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. Antihistamines appear to compete with histamine for receptor sites on effector cells. Brompheniramine also has anticholinergic (drying) and sedative effects. Among the antihistaminic effects, it antagonizes the allergic response (vasodilatation, increased vascular permeability, increased mucus secretion) of nasal tissue. Brompheniramine is well absorbed from the gastrointestinal tract, with peak plasma concentration after a single, oral dose of 4 mg reached in 5 hours; urinary excretion is the major route of elimination, mostly as products of biodegradation; the liver is assumed to be the main site of metabolic transformation.
