Medically reviewed by Drugs.com. Last updated on May 20, 2022.
Serious and sometimes fatal dermatologic reactions, including toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS), have been reported, especially in patients with the inherited allelic variant HLA-B*1502 who are almost exclusively of Asian ancestry. Avoid use of carbamazepine in patients testing positive for the allele unless the benefit clearly outweighs the risk. Discontinue if you suspect that the patient has a serious dermatologic reaction. Aplastic anemia and agranulocytosis have also been reported. Obtain a pretreatment complete blood count (CBC) and periodically monitor CBC. Consider discontinuing carbamazepine if significant bone marrow depression develops .
Commonly used brand name(s)
In the U.S.
- Carnexiv
Chemical Class: Dibenzazepine Carboxamide
Uses for carbamazepine
Carbamazepine injection is used as a replacement therapy for oral carbamazepine to treat adults with certain types of seizures (epilepsy). Carbamazepine works in the brain and nervous system to control seizures. Carbamazepine is an anticonvulsant.
Carbamazepine is to be given only by or under the direct supervision of your doctor.
Before using carbamazepine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For carbamazepine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to carbamazepine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of carbamazepine injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Although appropriate studies on the relationship of age to the effects of carbamazepine injection have not been performed in the geriatric population, ge..
