Carbidopa, entacapone, and levodopa

Generic name: carbidopa, entacapone, and levodopa [ KAR-bi-DOE-pa, en-TAK-a-pone, LEE-voe-DOE-pa ]
Brand names: Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75
Dosage form: oral tablet (12.5 mg-200 mg-50 mg; 18.75 mg-200 mg-75 mg; 25 mg-200 mg-100 mg; 31.25 mg-200 mg-125 mg; 37.5 mg-200 mg-150 mg; 50 mg-200 mg-200 mg)
Drug class:Dopaminergic antiparkinsonism agents

Medically reviewed by Drugs.com on Oct 4, 2021. Written by Cerner Multum.

What is carbidopa, entacapone, and levodopa (Stalevo)?

Carbidopa, entacapone, and levodopa (Stalevo) is a combination medicine used to treat Parkinson symptoms such as muscle stiffness, tremors, spasms, and poor muscle control.

Stalevo may also be used for purposes not listed in this medication guide.

Warnings

You should not use carbidopa, entacapone, and levodopa if you have narrow-angle glaucoma.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

You should not take this medicine if you are allergic to carbidopa, entacapone, or levodopa, or if you have:

• narrow-angle glaucoma.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have ever had:

• glaucoma;

• depression or other mental illness;

• a stomach ulcer; or

• liver disease.

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Ask your doctor about skin symptoms to watch for.

Tell your doctor if you are pregnant or breastfeeding.

How should I take Stalevo?

Follow all directions on your prescription label and read a...