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Chlorpheniramine, phenylephrine, and pyrilamine
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Chlorpheniramine, phenylephrine, and pyrilamine

Generic name: chlorpheniramine, phenylephrine, and pyrilamine [ KLOR-fe-NEER-a-meen, pir-IL-a-meen, FEN-il-EFF-rin ]
Brand names: Chlorex-A 12, Conal, MyHist-PD, Nalex A 12, Phena-Plus, ... show all 39 brands
Dosage forms: oral liquid (2 mg-10 mg-10 mg/5 mL; 2 mg-7.5 mg-12.5 mg/5 mL); oral suspension (2 mg-5 mg-12.5 mg/5 mL); oral suspension, extended release (8 mg-15 mg-12.5 mg/5 mL); oral tablet (2 mg-10 mg-10 mg); oral tablet, extended release (4 mg-10 mg-25 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Apr 25, 2022. Written by Cerner Multum.

What is chlorpheniramine, phenylephrine, and pyrilamine?

Chlorpheniramine and pyrilamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, phenylephrine, and pyrilamine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Chlorpheniramine, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide.

Warnings

You should not use chlorpheniramine, phenylephrine, and pyrilamine if you have severe coronary artery disease, diabetes, an overactive thyroid, asthma,