#
Estradiol
  • Drugs A to Z

Estradiol

Generic name: estradiol oral [ ess-tra-DYE-ole ]
Brand names: Estrace, Vivelle-Dot, Vivelle, Delestrogen, DepoEstradiol, ... show all 17 brands
Drug class:Estrogens

Medically reviewed by Kaci Durbin, MD. Last updated on Feb 21, 2022.

What is estradiol?

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. It is available as an oral tablet, a topical gel or patch, vaginal cream, or as an injection.

Estradiol is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women. Estradiol is also used to treat low estrogen levels in women with ovarian failure. It is also indicated to treat certain types of breast cancer and prostate cancer.

Estradiol may also be used for purposes not listed in this medication guide.

Warnings

You should not use estradiol if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.

Do not use estradiol if you are pregnant.

Estradiol may increase your risk of developing uterine cancer. Report any unusual vaginal bleeding right away.

Using this medicine can increase your risk of blood clots, stroke, or heart attack, or cancer of the breast, uterus, or ovaries. Estradiol should not be used to prevent heart disease, stroke, or dementia.

Have regular physical exams and mammograms