Gallium Citrate Ga 67
Dosage form: injection, solution
Drug class:Diagnostic radiopharmaceuticals
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
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Gallium Citrate Ga 67 Description
Gallium Citrate Ga 67 Injection is supplied in a 10 milliliter vial as an isotonic, sterile, non-pyrogenic solution. Each milliliter of the isotonic solution contains 74 megabecquerels (2 millicuries) of gallium Ga-67 on the calibration date as a complex formed from 8.3 nanograms gallium chloride Ga-67, 1.9 milligrams of sodium citrate dihydrate, 7.8 milligrams of sodium chloride and 0.9 percent benzyl alcohol (v/v) as a preservative. The pH is adjusted to between 5.5 to 8.0 with hydrochloric acid and/or sodium hydroxide solution.
Gallium Ga-67, with a half-life of 78.26 hours, is cyclotron produced by the proton irradiation of enriched zinc. At the time of calibration the drug contains no more than 0.02% gallium Ga-66 and no more than 0.2% zinc Zn-65. The concentration of each radionuclidic impurity changes with time. At expiration, the drug contains no more than 0.001% gallium Ga-66 and no more than 1.0% zinc Zn-65. No carrier has been added.
Gallium citrate has the following chemical structure:
Physical Characteristics
Gallium Ga-67 with a physical half-life of 78.26 hours1decays by electron capture to stable zinc Zn-67. Photons that are useful for imaging studies are listed in Table 1.
| Radiation | Mean Percent Per Disintegration | Energy (keV) |
| Gamma-2 | 2.9 | 91.3 |
| Gamma-3 | 35.7 | 93.3 |
| Gamma-4 |
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