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Glipizide and metformin
  • Treatments
  • Diabetes
  • Type 2

Glipizide and metformin

Generic name: glipizide and metformin [ GLIP-ih-zyd-and-met-FOR-min ]
Brand name: Metaglip
Dosage form: oral tablet (2.5 mg-250 mg; 2.5 mg-500 mg; 5 mg-500 mg)
Drug class:Antidiabetic combinations

Medically reviewed by Drugs.com on Mar 21, 2022. Written by Cerner Multum.

What is glipizide and metformin?

Glipizide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels.

Glipizide and metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. glipizide and metformin is not for treating type 1 diabetes.

Glipizide and metformin may also be used for purposes not listed in this medication guide.

Warnings

You should not use glipizide and metformin if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking glipizide and metformin.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

Before taking this medicine

You should not use glipizide and metformin if you are allergic to glipizide or metformin, or if you have:

  • severe kidney disease; or

  • metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking glipizide and metformin.

Tell your doctor if you have ever had:

  • kidney disease;

  • congestive heart failure, especially if you take digoxin (Lanoxin) or furosemide (Lasix);

  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;

  • liver disease;

  • heart disease; or

  • if you are over 80 years old and have not recently had your kidney function checked.

You may develop lactic acidosis, a dangerous build-up of lactic acid in yo...